Hybrid closed-loop therapy beneficial for children with type 1 diabetes

California News Times

(HealthDay) For children and adolescents with type 1 diabetes, hybrid closed-loop (HCL) therapy improves glycemic control and quality of life, according to a study published online on October 11. JAMA Pediatrics..

Mary B of the University of Western Australia. Abraham, Ph.D. And colleagues used HCL to examine the percentage of time spent in the target glucose range in a 6-month randomized clinical trial involving children and adolescents of type compared to current conventional treatments. I did. 1 Diabetes. Contains data for 135 patients: 68 were randomly assigned Control group And 67 to HCL group.

Researchers found that ITT analysis increased the time between baseline and end of the study (within the glucose range of 70-180 mg / dL) by 53.1-62.5%. 54.6 to 56.1 percent of the HCL and control groups (mean adjustment difference, 6.7 percent). There was no change in the time the patient spent in the hypoglycemic range (quality of life (difference, 4.4 points), diabetic distress. Both groups had episodes of severe hypoglycemia or diabetic ketoacidosis. There was no.

“The HCL system represents an important step in pursuing technological advances towards a fully automated closed-loop system,” the author writes.

Several authors have revealed relationships with the pharmaceutical and medical device industries. In-kind supply was provided by Medtronic through the provision of insulin pumps, sensors, and transmitters for research, and Roche Diabetes Care provided a glucose meter for research.


Hybrid closed-loop insulin therapy improves glycemic control


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